Network Science models the structure and dynamics of a wide variety of large-scale complex networks, including Internet connectivity, the WWW, peer-to-peer networks, and online social networks. Of particular relevance to the INFOCOM community, the design of efficient large-scale communication networks such as the Internet requires researchers to understand the interdependency between the underlying physical network and the information and social networks that it intends to support. This effort will require intimate knowledge of the emergent network properties, phase transitions, and dynamics of the component networks, as well as new research into the interaction between networks. A deeper understanding of such interdependency can only be achieved by closer interaction between network scientists, communication network designers, and social and behavioral scientists.